Ace (Angiotensin Converting Enzyme) Inhibitory Activity of Apple Extract

Abstract

Hypertension is causative risk issue for disorder. RAAS (Renin-Angiotensin-Aldosterone-System) is one among the components that contribute in maintenance of circulatory pressure and electrolytes balance. ACE (Angiotensin changing Enzyme) is main player of RAAS system. Purpose of the study was to try to find ACE repressive activity of apple extract. varied dosages of the extract were used and ACE activity was calculable. therefore, on discover the causative issue phytochemical examination of apple extract was done. Finding of this study shows that significantly (p<0.001) ACE repressive activity of apple extract in a dose dependent manner. Highest ability to inhibit ACE activity was seen in 500 l extract of apple.